Patent Prosecution (chemical, biotech, pharmaceutical and medical)

Patentability Opinions

Freedom to Practice Opinions

Validity Opinions

• Ohio, 2000

• Northern Kentucky University, Salmon P. Chase College of Law, J.D., 2000
• Ohio State University, Post-Doctoral Fellow, 1990, in Physical Organic Chemistry
• University of Cincinnati, Ph.D., 1989, in Organic Chemistry
• University of Cincinnati, B.S., 1984, with honors in Chemistry

Karlyn is a member at Frost Brown Todd LLC.  Her areas of expertise are patent prosecution in small molecule (organic), pharmaceutical, and polymer chemistry; ANDA-related work for generic pharmaceuticals (paragraph III and IV filings); experience in therapeutic areas including oncology, cardiovascular and antipsychotic drugs; freedom to practice opinions, validity opinions and patentability opinions; licensing agreements (joint development, joint venture, letter of intent, confidentiality agreement); due diligence review of intellectual property assets and patent portfolio management.  Karlyn represents a variety of clients including corporate clients, university researchers, pharmaceutical companies, and entrepreneurial start-up companies.  She is admitted to practice in Ohio and before the United States Patent and Trademark Office.  Prior to joining Frost Brown Todd, Karlyn was an Associate Professor at Northern Kentucky University.  Karlyn has also worked as a research scientist prior to her academic career.

• Chambers USA,® America's Leading Business Lawyers, 2005-2011
• Selected for inclusion in Ohio Super Lawyers® and Cincinnati Magazine "Rising Star," Intellectual Property Law, 2006
• The Best Lawyers in America® 2012

• Ohio State Bar Association
• American Bar Association
• United States Patent and Trademark Office
• American Intellectual Property Law Association, Member
• American Chemical Society, Member
• Cincy IP, Member
• Cincinnati Bar Association,  Member

Photochemistry and Radical Cation Chemistry of Aryl Enones: A Comparison of Mechanistic Pathways. Pacifichem '95 (Pacific Basin Chemistry Conference), Honolulu, HI, December 17-22, 1995. 

Dihydrodioxins: Masked Ortho-Quinones as DNA Cleaving Agents.  Eighth Conference of the Inter-American Photochemical Society, Foz do Iguacu, Brazil, May 19-24, 1996.

Dihydrodioxins: Photochemically Activated Masked DNA Cleaving Agents.  The Effects of Quinone Fluorination.  213th ACS National Meeting, San Francisco, CA, April 13-17, 1997.

1,4-Dihydrodioxins as Synthetic Photonucleases: Effect of Substitution and Potential for Site-Specific DNA Scission. Gordon Conference on Organic Photochemistry, Salve Regina University, Newport, RI, July 19-24, 1997.

Benzoquinone-olefin Exciplexes: The Observation and Chemistry of the p-Benzoquinone-tetraphenylallene Exciplex, J. Am. Chem. Soc., 1990, 112, 3700.  K. A. Schnapp, R. M. Wilson, D. M. Ho, R. A. Caldwell, D. Creed.

Remarkable Catalysis of Intersystem Crossing of Singlet Pentafluorophenylnitrene, J. Am. Chem. Soc., 1991, 113, 3209.  Russell Poe, Jennifer Grayzer, M. Jennifer T. Young, Elisa Leyva, Karlyn A. Schnapp, Matthew S. Platz.

High Intensity Laser Photochemistry of Organic Molecules in Solution.  Chemical Reviews, 1993, 93, 223, R. Marshall Wilson, Karlyn A. Schnapp.

Exploratory Photochemistry of Fluorinated Aryl Azides; Implications for the Design of Photoaffinity Labelling Reagents.  Bioconjugates,  1993 4, 172, Karlyn A. Schnapp, Russell Poe, Elisa Leyva, N. Soundararajan, Matthew S. Platz.

High-Intensity, Laser-Jet Photochemistry: Photodecarboxylation of 3,3-diphenyl-1H,3H-naphtho[c,d]pyran-1-one. J. Chem. Soc., Chem. Commun.. 1997, 149-50. R. Marshall Wilson, Karlyn A. Schnapp, Martin Gloss, Cornelia Bohne, Andrew C. Dixon.